🧴 Instrument Disinfectant Liquids (Glutaraldehyde-Based and Alcohol-Containing) – Production, Formulation and Properties
Overview:
Glutaraldehyde-Based and Alcohol-Containing Instrument Disinfectant Liquids are advanced sterilizing formulations designed for rapid and efficient disinfection of medical, dental, and laboratory instruments.
They combine the strong biocidal action of glutaraldehyde with the fast-drying and degreasing properties of alcohols, achieving high-level disinfection (HLD) suitable for surgical tools, endoscopes, and precision instruments.
This dual-action system ensures broad-spectrum antimicrobial protection, shorter contact time, and surface compatibility for professional healthcare use.
Production and Formulation:
The formulation combines glutaraldehyde as the primary active disinfectant with alcohols (ethanol or isopropanol) to enhance penetration, evaporation rate, and quick sterilization.
It is stabilized with buffers and corrosion inhibitors to maintain pH and prevent metal degradation.
Typical composition includes:
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Active Ingredient: Glutaraldehyde (1–3%) for powerful microbial inactivation.
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Alcohol Phase: Ethanol or isopropyl alcohol (20–40%) for rapid surface sterilization.
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Buffer System: Sodium phosphate or bicarbonate for pH stabilization (7.0–8.0).
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Non-ionic Surfactants: To enhance cleaning and prevent residue.
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Chelating Agents: EDTA or citric acid to improve performance in hard water.
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Corrosion Inhibitors: Protects metal instruments and stainless steel.
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Deionized Water: Solvent and dilution medium.
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Fragrance (optional): Mild or neutral scent to reduce aldehyde odor.
Manufacturing Process:
The components are mixed under moderate agitation, maintaining a controlled temperature to prevent glutaraldehyde polymerization.
After blending, pH is adjusted, and the product is filtered and filled into HDPE or amber chemical-resistant containers to ensure light and oxidation protection.
Properties:
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Appearance: Clear, colorless to pale yellow liquid
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Odor: Mild aldehydic-alcoholic scent
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pH Range: 7.0–8.0 (buffered neutral)
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Foam Level: Low
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Antimicrobial Spectrum: Bactericidal, virucidal, fungicidal, and sporicidal
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Residue: Leaves no sticky or oily film after rinsing
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Drying Rate: Rapid, due to alcohol phase
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Shelf Life: 24–30 months
Advantages:
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Dual-action disinfection: Combines aldehyde sterilization with alcohol speed
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Fast-drying and residue-free finish
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Effective against spores, bacteria, fungi, and viruses
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Enhanced penetration into complex instruments
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Non-corrosive and safe for metal, plastic, and glass
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Stable under temperature variations
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Ideal for immersion, spraying, or wiping applications
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Compliant with EN and ISO disinfection standards
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Suitable for use in hospitals, dental clinics, and laboratories
Summary:
Glutaraldehyde-Based and Alcohol-Containing Instrument Disinfectant Liquids deliver high-speed, high-level sterilization performance for professional healthcare and laboratory environments.
Their dual chemical action ensures deep cleaning, rapid evaporation, and broad-spectrum antimicrobial protection, all while maintaining material safety and operator comfort.
These formulations represent an optimal balance between chemical strength and safety, supporting reliable and efficient disinfection cycles.
