⚗️ Instrument Disinfectant Liquids (Glutaraldehyde-Based and Alcohol-Free) – Production, Formulation and Properties
Overview:
Instrument Disinfectant Liquids (Glutaraldehyde-Based and Alcohol-Free) are powerful sterilizing and disinfecting solutions specially formulated for medical, dental, and laboratory instruments.
These disinfectants are designed to deliver high-level disinfection (HLD) without using alcohol, ensuring complete microbial inactivation while maintaining instrument integrity and longevity.
Their broad-spectrum antimicrobial properties make them suitable for critical and semi-critical instruments, including surgical tools, endoscopes, and reusable medical devices.
Production and Formulation:
The formulation of glutaraldehyde-based, alcohol-free disinfectant liquids focuses on achieving high biocidal performance, chemical stability, and material compatibility.
Typical composition includes:
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Active Ingredient: Glutaraldehyde (2–5%) as the primary disinfectant and sterilizing agent.
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Buffering System: Sodium bicarbonate or phosphate buffers to stabilize pH (7.0–8.5).
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Surfactants: Mild non-ionic surfactants to enhance wetting and penetration.
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Corrosion Inhibitors: Protects metals and instrument joints from oxidation.
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Chelating Agents: EDTA or citric acid to improve cleaning efficiency.
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Deionized Water: Used as solvent and diluent for formulation stability.
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Fragrance (Optional): Low-odor or odor-neutralized additives to minimize harsh smell.
Manufacturing Process:
All ingredients are mixed under controlled agitation until uniform dispersion is achieved.
The glutaraldehyde phase is introduced at the final step to maintain maximum activity and pH balance.
The solution is filtered and packed into HDPE or amber bottles to prevent light degradation.
Properties:
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Appearance: Clear or slightly yellowish liquid
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Odor: Mild antiseptic or neutralized aldehyde scent
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pH Range: 7.0–8.5 (buffered)
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Foam Level: Very low
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Antimicrobial Activity: Broad-spectrum bactericidal, fungicidal, virucidal, and sporicidal
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Compatibility: Safe for stainless steel, glass, ceramics, and most plastics
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Residue: Non-sticky and easily rinsable
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Shelf Life: 24 months (unactivated), 14–30 days (activated use solution)
Advantages:
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High-level disinfection and sterilization capability
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Alcohol-free formula prevents rapid evaporation and material damage
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Effective against resistant microorganisms and spores
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Stable pH for extended product life
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Non-corrosive to surgical and diagnostic instruments
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Low foaming for easy rinsing and immersion cleaning
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Suitable for manual or ultrasonic disinfection systems
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Cost-effective and compliant with medical hygiene standards (EN 14885, EN 13727, EN 13624)
Summary:
Glutaraldehyde-Based and Alcohol-Free Instrument Disinfectant Liquids ensure safe, effective, and residue-free sterilization of medical and laboratory equipment.
They deliver broad-spectrum antimicrobial protection, maintaining instrument functionality and surface integrity.
Their non-alcoholic, pH-balanced composition provides maximum disinfection efficiency with minimal odor and corrosion risk, making them essential for hospitals, laboratories, and dental clinics.
