CHLORHEXIDINE GLUCONATE SPECIFICATION / MSDS / CAS NUMBER

 

Empirical Formula CAS #
C₂₂H₃₀Cl₂N₁₀ · 2HCl 3697-42-5

Description
Overview

This product has been discontinued.

 

An anti-microbial agent that acts as an inhibitor of MMP-2 and MMP-9; however, MMP-2 is more sensitive to chlorhexidine than MMP-9. Inhibits the collagenase activity of MMP-8 released by PMA-triggered polymorphonuclear leukocytes (PMNs) in a dose-dependent manner. CHX may possibly act through a cation-chelating mechanism.
Note: presence of CaCl2 in the medium blocks the inhibitory activity of CHX.
Catalogue Number  
Brand Family Calbiochem®
Synonyms 1,6-bis[Nʹ-(p-Chlorophenyl)-N⁵-biguanido]hexane, 2HCl, CHX

References
References Gendron, R., et al. 1999. Clin. Diagn. Lab. Immunol. 6, 437.

Product Information
CAS number 3697-42-5
Form White solid
Hill Formula C₂₂H₃₀Cl₂N₁₀ · 2HCl
Chemical formula C₂₂H₃₀Cl₂N₁₀ · 2HCl
Hygroscopic Hygroscopic
Structure formula Image Structure formula Image

Biological Information
Primary Target MMP-2, MMP-9
Secondary target MMP-8 collagenase activity
Purity ≥95% by titration

Safety Information according to GHS
RTECS XA5285000

Safety Information
R Phrase R: 36/37/38

Irritating to eyes, respiratory system and skin.
S Phrase S: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.

Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage +2°C to +8°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special Instructions Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

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